1 1000 2 http://oer.uinsyahada.ac.id/files/original/cc169acc716b79b35248cbb6e756d435.pdf d7b615d759f2a68bbe46d067e6777494 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 616 Diseases Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Head and Neck Cancers Subject The topic of the resource Cancers Description An account of the resource 1. A variety of different malignancies fall into the category of “Head and. Neck Cancers”. This chapter focuses on upper aerodigestive tract cancer. 2. Tobacco and alcohol use and human papillomavirus infection are common causes of head and neck cancers. 3. Most head and neck cancers are squamous cell carcinomas. 4. Treatment of head and neck cancers commonly requires some combination of surgery, radiation, and chemotherapy. Close cooperation between otolaryngologists, radiation oncologists, and medical oncologists is mandatory for successful treatment of these cancers. 5. Preservation of organ function in addition to cure of cancer, is an important goal of treatment. 6. Any patient with persistent symptoms of sore throat, hoarseness, difficulty swallowing or an enlarged cervical lymph node should be evaluated for possible head and neck cancer. Creator An entity primarily responsible for making the resource James Liebmann, MD, Ali Akalin MD, PhD., Liana Puscas, MD, MHS., Andrew Chen MD., Richard S. Pieters, MD Source A related resource from which the described resource is derived https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1021&context=cancer_concepts Publisher An entity responsible for making the resource available - Date A point or period of time associated with an event in the lifecycle of the resource 2019 Contributor An entity responsible for making contributions to the resource Baihaqi Rights Information about rights held in and over the resource Creative Commons Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Textbooks http://oer.uinsyahada.ac.id/files/original/f28ee74e0bf950b31700a82b102e5037.pdf 63674bc17c21c2dc63302ed50d5da2e0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 616 Diseases Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Metastatic Extramammary Paget's Disease: Pathogenesis and Novel Therapeutic Approach Subject The topic of the resource Metastatic Extramammary Paget's Disease, Pathogenesis and Novel Therapeutic Approach Description An account of the resource Extramammary Paget's disease (EMPD) is a rare, slow-growing, cutaneous adenocarcinoma that usually originates in the anogenital area and axillae outside the mammary glands. EMPD mostly progresses slowly and is often diagnosed as carcinoma in situ; however, upon becoming invasive, it promptly and frequently metastasizes to regional lymph nodes, leading to subsequent distant metastasis. To date, several chemotherapy regimens have been used to treat metastatic EMPD; however, they present limited effect and patients with distant metastasis exhibit a poor prognosis. Recently, basic and translational investigative research has elucidated factors and molecular mechanisms underlying the promotion of metastasis, which can lead to targeted therapy-based emerging treatment strategies. Here, we aim to discuss current therapies and their limitations; advancements in illustrating mechanisms promoting invasion, migration, and proliferation of EMPD tumor cells; and future therapeutic approaches for metastatic EMPD that may enhance clinical outcomes. Creator An entity primarily responsible for making the resource Keitaro Fukuda, Takeru Funakoshi Source A related resource from which the described resource is derived https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4366&context=oapubs Publisher An entity responsible for making the resource available UMMS Authors Date A point or period of time associated with an event in the lifecycle of the resource 2018 Contributor An entity responsible for making contributions to the resource Baihaqi Rights Information about rights held in and over the resource Creative Commons Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource Publications